3. When any one attains a good thing that he was not intending, that is by luck and chance. If then he whose intention is turned away from the last end were to gain that last end, it would be by luck and chance, -- which is an absurd thing to suppose, seeing that the last end is a good of intelligence, and luck and chance are inconsistent with intelligent action, because chance events come about without the direction of intelligence: it is absurd then to suppose intelligence gaining its end by an unintelligent method. He then will not gain his end, who by sinning mortally has his intention turned away from his last end.
5. In an orderly course of means leading up to an end such a relation obtains that, if the end is or is to be, the means thereto must be: if the means to the end are not forthcoming, neither will the end be forthcoming: for if the end could be secured without the means to the end being taken, it would be labour lost to seek the end by the taking of such means. But it is by arts of virtue, the chief element in which is an intention of the due end, that man attains to his last end and happiness (Chap. CXLI). Whoever then acts against virtue, and turns his back on his last end, it is proper for him to suffer deprivation of that end.
Hence it is said: Depart from me, all ye workers of iniquity (Matt. vii, 23).
3.143 : That not all Punishments nor all Rewards are Equal
3.145 : That the Punishment whereby one is deprived of his Last End is Interminable