Welcome to the Genomics & Bioinformatics Core Facility website
The Genomics Core provides capillary-based Sanger sequencing and DNA fragment length analysis, high-throughput next generation sequencing (454 and Illumina platforms), as well as Affymetrix and NimbleGen microarray services. The Bioinformatics Core offers consultation, data analysis and management, tools, custom development, and access to computing resources. The core is also committed to education and training, so workshops and training will be offered to core users.
Consultation with Genomics Core personnel (Dr. John Tan) is necessary before any microarray or next-generation sequencing services will be provided. It is necessary to consult with Bioinformatics Core personnel (Dr. Erliang Zeng) for data analysis support. PIs submitting grants that will incorporate work through the core facility are strongly encouraged to speak with core personnel (Dr. Michael Pfrender, Dr. Tan, or Dr. Zeng) to discuss experiments and obtain a letter of support. Additionally, the Genomics & Bioinformatics Core Facility is an approved Indiana CTSI core facility.
Our policies for collaborative core users are available here.
Recent updates5/2/2013 - We have a new order form for full-service capillary sequencing services. Please use this form for all full-service orders and follow the instructions on the order form.
4/18/2013 - Sequenom will present a technology seminar about their MassARRAY system on Wednesday, April 24th @ 1pm in Galvin 298 (2nd floor conference room). More information is available in this flyer.
2/11/2013 - The Indiana CTSI announced their Spring Pilot Funding for Research Use of Core Facilities funding opportunity. This competition is open to investigators from all Indiana CTSI partner institutions. Investigators can request up to $10,000 in core services from approved CTSI cores including the Notre Dame Genomics and Bioinformatics Core. The submission deadline is April 8th at 5pm.
12/5/2012 - Our Illumina MiSeq sequencer has been upgraded to enable 250 bp paired-end reads. The online price list has been updated to include this service option.
11/1/2012 - Roche NimbleGen has stopped accepting orders for their microarray platform. We will not be able to obtain any new NimbleGen microarrays in the future, but we can continue to run experiments for any microarrays which are already in your possession.
9/17/2012 - The university has implemented CORES software for all of the University's core facilities and shared resources. Orders must be placed through this system; please view the CORES website for additional information about this system.
Older updates- Our redo policy for full service Sanger sequencing is now posted on the Services page.
- Sequencher DNA Sequence Assembly Software (Windows only; please view the Services page for other multi-platform alternatives) is available for on-campus users through the OIT Software Download page. To use this software, a computer must be connected to the Notre Dame network and have KeyAccess Client software installed (also available through the OIT Software Download page).