Gao Research Group
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    2016 Group Picture

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    June 2016 - Group Lunch

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    Dec. 2015 Group Dinner

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    Dec. 2014 Group Picture

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    Dec. 2014 Group Dinner

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    March 2014 Group Ski

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    July 2014 Doyun Farewell

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    Dec 2013 Group Dinner

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    Dec 2012 Group Dinner

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    Aug 2012 group picture

Research Goals
News
  • August-2016: Research paper by Lei is published in Polymer Chemistry. Congratulations!
  • August-2016: Research paper by Xiaofeng is published in Macromolecules. Congratulations!
Open Positions:
  • Graduate Students
    The Gao group is currently seeking motivated, ambitious graudate students. Students in the Gao group will have opportunity to acquire skills that encompass the areas of advanced organic/ polymer synthesis, characterization, catalysis, and molecular spectroscopy. Group members are encouraged to foster new ideas that are tailored to satisfy their current and future interests. Applicants should apply directly to the Department of Chemistry & Biochemistry via the main website and contact Dr. Gao via email as well.
  • Undergraduate Applicants
    Undergraduate students with enthusiasm in organic chemistry and polymer materials are welcome to contact Dr. Gao.
Polymers have been at the forefront of soft nanomaterials research due to their advantages including inexpensive feedstocks, versatile chemical compositions and nanometer-sized scale. In addition to well-established commodity applications, synthetic and biological macromolecules have been recently explored in specialty areas as diverse as nanoelectronics, data storage devices, new energy, healthcare, and biotechnology. These emerging markets generated new directions in fundamental and applied polymer research to design macromolecules with controlled chemical compositions, molecular weights and distributions, site-specific functionalities and architectures, which represent a robust multidisciplinary area, i.e., macromolecular engineering.

Our research embraces all the aspects of a successful materials design, from building structure-tailored polymers to analyzing their supermolecular organization and finally to testing their macroscopic properties. The main thrust is to design functional polymers and understand their structure-property relationships. These soft nanomaterials will meet critical challenges in broad fields of nanotechnology and biomedical sciences, including nanodevice construction, gas separation, catalysis, drug delivery and molecular electronics. The multidisciplinary nature in this research program allows students to acquire diverse synthetic and analytical skills and develop broad scientific vision in organic chemistry, polymer chemistry and materials science.

Our Team


Dr. Haifeng Gao
Assistant Professor

[Click for full CV]
305C McCourtney Hall
Department of Chemistry and Biochemistry
University of Notre Dame
Notre Dame, IN 46556
Tel: 574-631-8023, Fax: 574-631-6652
Email: hgao(at)nd.edu

Education
  • Postdoctoral Fellow, University of California Berkeley 01/2009 - 05/2011
  • Ph.D. (Chemistry) Carnegie Mellon University 12/2008
  • B.S. (Polymer Chemistry) Fudan University, Shanghai, China 06/2000

  • Appointment & Professional Experience
  • Assistant Professor, Dept. of Chemistry & Biochemistry, University of Notre Dame 07/2011 - Present
  • Postdoctoral Associate, UC Berkeley and Lawrence Berkeley National Laboratory 01/2009 - 05/2011
  • Research Assistant, Carnegie Mellon University 2004 - 2008

  • Awards and Honors
  • NSF CAREER award 2016
  • Thieme Chemistry Journal Awardees 2015
  • Army Young Investigator Program (YIP) award 2014
  • Senior Visiting Scholar of Key Laboratory in Fudan University, China 2013
  • UMass MRSEC Young Investigator Award 2013
  • AkzoNobel Award for Outstanding Graduate Research in Polymer Chemistry, ACS 2010
  • Guy C. Berry Graduate Research Award at Carnegie Mellon University 2008
  • Student Research Award at ACS Polymer Group (Pittsburgh Section) 2008
  • Chinese Government Award for Outstanding Self-Financed Students Abroad 2007
  • McWilliams Fellowship at Carnegie Mellon University 2007

  • Courses at Notre Dame
    (CHEM20283) Organic Chemistry II: Organic Reactions and Applications - 2016, 2015, 2014
    (CHEM40438/60438) Polymer Chemistry: from Principle to Practice - 2016, 2015, 2013
    (CHEM10182) Organic Chemistry I: Organic Structure and Mechanism - 2014, 2013
    (CHEM90638) Special Topics of Organic Chemistry: Polymer Chemistry - 2012, 2011



    Dr. Yi Shi
    PD

    326 McCourtney Hall
    Tel: 574-631-0967
    Yi.Shi.27(at)nd.edu

    Dr. Lei Zou, Postdoc
    PD

    326 McCourtney Hall
    Tel: 574-631-0967
    Lei.Zou.9(at)nd.edu

    Dr. Daqiao Hu
    Visiting Scientist

    326 McCourtney Hall
    Tel: 574-631-0967
    Daqiao.Hu.59(at)nd.edu

    Xiaofeng Wang
    GS

    326 McCourtney Hall
    Tel: 574-631-0967
    xwang26(at)nd.edu

    Robert Graff
    GS

    326 McCourtney Hall
    Tel: 574-631-0967
    rgraff(at)nd.edu

    Xiaosong Cao
    GS

    326 McCourtney Hall
    Tel: 574-631-0967
    xcao(at)nd.edu

    Weiping Gan
    GS

    326 McCourtney Hall
    Tel: 574-631-0967
    Weiping.Gan.3(at)nd.edu

    Timothy Cuneo
    GS

    326 McCourtney Hall
    Tel: 574-631-0967
    Timothy.J.Cuneo.5@nd.edu

    Hannah Naguib
    UG

    326 McCourtney Hall


    Publications

    +
    2016

    73. Xiaofeng Wang, Yi Shi, Robert W. Graff, Xiaosong Cao, and Haifeng Gao, Synthesis of Hyperbranched Polymers with High Molecular Weight in the Homopolymerization of Polymerizable Trithiocarbonate Transfer Agent without Thermal Initiator, Macromolecules 2016, 49, 6471-6479.

    72

    72. Lei Zou; Yi Shi; Xiaosong Cao; Weiping Gan; Xiaofeng Wang; Robert Graff; Daqiao Hu; Haifeng Gao, Synthesis of Acid-Degradable Hyperbranched Polymers by Chain-Growth CuAAC Polymerization of an AB3 Monomer, Polym. Chem. 2016, 7, 5512 - 5517.

    72

    71. Xiaosong Cao, Yi Shi, Weiping Gan, Hannah Naguib, Xiaofeng Wang, Robert W. Graff, and Haifeng Gao, Effect of Monomer Structure on the CuAAC Polymerization To Produce Hyperbranched Polymers, Macromolecules 2016, 49, 5342-5349.

    71

    70. Yi Shi; Xiaosong Cao; Shuangjiang Luo; Xiaofeng Wang; Robert W. Graff; Daqiao Hu; Ruilan Guo; Haifeng Gao, Investigate the Glass Transition Temperature of Hyperbranched Copolymers with Segmented Monomer Sequence, Macromolecules 2016, 49, 4416-4422.

    70

    69. Chen Qu; Yi Shi; Benxin Jing; Haifeng Gao; Yingxi Zhu, Probing the Inhomogeneous Charge Distribution on Annealed Polyelectrolyte Star Polymers in Dilute Aqueous Solutions, ACS Macro Letters 2016, 5, 402-406.

    70

    68. Yi Shi, Xiaosong Cao, Haifeng Gao, The Use of Azide-Alkyne Click Chemistry in Recent Syntheses and Applications of Polytriazole-based Nanostructured Polymers, Nanoscales, 2016, 8, 4864-4881.

    70

    67. Xiaosong Cao#; Yi Shi#; Xiaofeng Wang; Robert W. Graff; Haifeng Gao, Design A Highly Reactive Trifunctional Core Molecule to Obtain Hyperbranched Polymers with Over A Million Molecular Weight in One-pot Click Polymerization, Macromolecules 2016, 49, 760-766.

    70

    +
    2015

    66. S. Misra; X. Wang; I. Srivastava; M. Imgruet; R.W. Graff; A. Ohoka; T. Kampert; H. Gao; D. Pan, Combinatorial Therapy for Triple Negative Breast Cancer using HyperStar Polymer-based Nanoparticles, Chem. Commun. 2015, 51, 16170-16173.

    70

    65. Robert W. Graff; Yi Shi; Xiaofeng Wang; Haifeng Gao, Comparison of Loading Efficiency between Hyperbranched Polymers and Crosslinked Nanogels at Various Branching Densities, Macromol. Rapid Commun. 2015, 36, 2076-2082.

    70

    64. Xiaofeng Wang; Robert W. Graff; Yi Shi; Haifeng Gao, One-pot synthesis of hyperstar polymers via sequential ATRP of inimers and functional monomers in aqueous dispersed media, Polym. Chem. 2015, 6, 6739-6745.

    70

    63. Yi Shi; Robert W. Graff; Xiaosong Cao; Xiaofeng Wang, Haifeng Gao, Chain-Growth Click Polymerization of AB2 Monomers to Produce Hyperbranched Polymer with Low Polydispersity in One-Pot, Angew. Chem., Int. Ed. 2015, 7631–7635.

    70

    62. Guolin Lu; Hao Liu; Haifeng Gao; Chun Feng; Yongjun Li; Xiaoyu Huang, Construction of semi-fluorinated amphiphilic graft copolymer bearing a poly(2-methyl-1,4-bistrifluorovinyloxybenzene) backbone and poly(ethylene glycol) side chains via the grafting-onto strategy, RSC Advances 2015, 5, 39668-39676.

    70

    61. Qiao An; Zifeng Li; Robert Graff; Jia Guo; Haifeng Gao; Changchun Wang, Core-Double-Shell Fe3O4@Carbon@Poly(InIII-carboxylate) Microspheres: Cycloaddition of CO2 and Epoxides on Coordination Polymer Shells Constituted by Imidazolium-Derived AlIII–Salen Bifunctional Catalysts, ACS Appl. Mater. Interfaces 2015, 7, 4969-4978.

    70

    60.Robert W. Graff; Xiaofeng Wang; Haifeng Gao, Exploring Self-Condensing Vinyl Polymerization of Inimers in Microemulsion To Regulate the Structures of Hyperbranched Polymers, Macromolecules 2015, 48, 2118–2126.

    70

    59.Zhi Guo, Doyun Lee, Haifeng Gao, Libai Huang, Exciton Structure and Dynamics in Solution Aggregates of a Low-bandgap Copolymer, J. Phys. Chem. B 2015, 119, 7666–7672.

    70

    58. Xiaofeng Wang; Yi Shi; Robert W. Graff; Doyun Lee; Haifeng Gao, Developing Recyclable pH-Responsive Magnetic Nanoparticles for Oil-Water Separation, Polymer 2015 72, 361-367.

    70

    57. Doyun Lee, Chengyi Zhang, Haifeng Gao, Amine-Functionalized Mesoporous Polymer Network for Highly Selective Absorption of CO2 over N2, Macromol. Chem. Phys. 2015, 216, 489-494.

    70

    56. Yi Shi; Xiaofeng Wang; Robert W. Graff; William A. Phillip; Haifeng Gao, Synthesis of degradable molecular brushes via a combination of ring-opening polymerization and click chemistry, J. Polym. Sci., Part A: Polym. Chem. 2015, 53, 239.

    70

    +
    2014

    55. Sahadevan Rajesh; Yu Yan; Hsueh-Chia Chang; Haifeng Gao; William A. Phillip, Mixed Mosaic Membranes Prepared by Layer-by-Layer Assembly for Ionic Separations, ACS Nano 2014, 8, 12338-12345.

    70

    54. Zhi Guo, Doyun Lee, Joseph Strzalka, Haifeng Gao, Libai Huang, Ali M. Khounsary and Tengfei Luo, Thermal Conductivity of Organic Bulk Heterojunction Solar Cells: An Unusual Binary Mixing Effect, Phys. Chem. Chem. Phys, 2014, 16, 26359.

    70

    53. Dian Li; Yuting Zhang; Sha Jin; Jia Guo; Haifeng Gao; Changchun Wang, Development of a redox/pH dual stimuli-responsive MSP@P(MAA-Cy) drug delivery system for programmed release of anticancer drugs in tumour cells, J. Mater. Chem. B 2014, 2, 5187.

    70

    52. Zhi Guo; Doyun Lee; Richard D. Schaller; Xiaobing Zuo; Byeongdu Lee; TengFei Luo; Haifeng Gao; Libai Huang, Relationship between Interchain Interaction, Exciton Delocalization, and Charge Separation in Low-Bandgap Copolymer Blends, J. Am. Chem. Soc. 2014, 136, 10024.

    70

    51. Zhi Guo, Doyun Lee, Yi Liu, Fangyuan Sun, Haifeng Gao, Burns Peter, Libai Huang, and Tengfei Luo, Tuning the Thermal Conductivity of Solar Cell Polymers through Side Chain Engineering, Phys. Chem. Chem. Phys, 2014, 16, 7764.

    70

    50. Doyun Lee, Chengyi Zhang and Haifeng Gao, Facile Production of Polypyrrole Nanofibers Using Freeze-Drying Method, Macromol. Chem. Phys. 2014, 215, 669.

    70

    49. Chengyi Zhang, Xiaofeng Wang, Ke Min, Doyun Lee, Chuan Wei, Hannah Schulhauser and Haifeng Gao, Developing Porous Honeycomb Films Using Miktoarm Star Copolymers and Exploring Their Application in Particle Separation, Macromol. Rapid Commun. 2014, 35, 221.

    70

    +
    2013
    +
    2012
    Publications Before 2011
    +
    2011
    +
    2010
    +
    2009

    36. Haifeng Gao; Ke Min; Krzysztof Matyjaszewski, Gelation in ATRP Using Structurally Different Branching Reagents: Comparison of Inimer, Divinyl and Trivinyl Cross-linkers, Macromolecules 2009, 42, 8039.

    35. Haifeng Gao; Piotr Polanowski; Krzysztof Matyjaszewski, Gelation in Living Copolymerization of Monomer and Divinyl Cross-Linker: Comparison of ATRP Experiments with Monte Carlo Simulations, Macromolecules 2009, 42, 5925.

    34. Sidi A. Bencherif; Haifeng Gao; Abiraman Srinivasan; Daniel J. Siegwart; Jeffrey O. Hollinger; Newell R. Washburn; Krzysztof Matyjaszewski, Cell-Adhesive Star Polymers Prepared by ATRP, Biomacromolecules 2009, 10, 1795.

    33. Haifeng Gao; Krzysztof Matyjaszewski, High-Yield Synthesis of Uniform Star Polymers-Is Controlled Radical Polymerization Always Needed? Chem. Eur. J. 2009, 15, 6107.

    32. Haifeng Gao; Krzysztof Matyjaszewski, Synthesis of Functional Polymers with Controlled Architecture by CRP of Monomers in the Presence of Cross-linkers: From Stars to Gels, Prog. Polym. Sci. 2009, 34, 317.

    31. Shigeki Ohno; Haifeng Gao; Brian Cusick; Tomasz Kowalewski; Krzysztof Matyjaszewski, Methacryloyl and/or Hydroxyl End-Functional Star Polymers Synthesized by ATRP using the Arm-First Method, Macromol. Chem. Phys. 2009, 210, 421.

    30. Ke Min; Haifeng Gao; Jeong Ae Yoon; Wei Wu; Tomasz Kowalewski; Krzysztof Matyjaszewski, One-Pot Synthesis of Hairy Nanoparticles by Emulsion ATRP, Macromolecules 2009, 42, 1597.

    29. Wenwen Li; Haifeng Gao; Krzysztof Matyjaszewski, Influence of Initiation Efficiency and Polydispersity of Primary Chains on Gelation during Atom Transfer Radical Copolymerization of Monomer and Cross-Linker, Macromolecules 2009, 42, 927.

    28. Byeong-Su Kim; Haifeng Gao; Avni A. Argun; Krzysztof Matyjaszewski; Paula T. Hammond, All-Star Polymer Multilayers as pH-Responsive Nanofilms, Macromolecules 2009, 42, 368.

    +
    2008
    +
    2007
    +
    2006
    +
    2005
    +
    2004

    3. Haifeng Gao; Changchun Wang; Wuli Yang; Shoukuan Fu, Preparation of A Water-Soluble Fluorescent Polymer, J. Macromol. Sci., Pure Appl. Chem. 2004, A41, 357

    +
    2002

    2. Haifeng Gao; Yiqiang Zhao; Shoukuan Fu; Bin Li; Minqian Li, Preparation of A Novel Polymeric Fluorescent Nanoparticles, Colloid Polym. Sci. 2002, 280, 653.

    1. Liusheng Zha; Haifeng Gao; Wuli Yang; Xinguo Jiang; Shoukuan Fu, Polymer Nanoparticles for Drug Delivery, Polymer Bulletin-Chinese 2002, 59, 24


    Book Chapters

    6. Y. Shi, R.W. Graff, H. Gao*, Recent Progress on Synthesis of Hyperbranched Polymers with Controlled Molecular Weight Distribution, in ACS Symp. Ser. 2014, Vol. 1188, 135-147.

    5. H. Gao*, N. Chan, J.K. Oh, K. Matyjaszewski, Designing Hydrogel by ATRP, Editor: Xian Jun Loh, Date of publication: Jan 2015, Springer

    4. C. Wei, H. Gao*, Star Polymers as Unimolecular Containers, in Encyclopedia of Polymeric Nanomaterials, edited by Shiro Kobayashi and Klaus Müllen, Springer-Verlag Berlin Heidelberg 2014.

    3. H. Gao; W. Li; K. Min; K. Matyjaszewski, Gelation in Atom Transfer Radical Copolymerization with A Divinyl Cross-linker, in ACS Symp. Ser. 2009, Vol. 1023, 203

    2. N.V. Tsarevsky; K. Min; N.M. Jahed; H. Gao; K. Matyjaszewski, Degradable Polymers and Materials - Principles and Practice, in ACS Symp. Ser. 2006, Vol. 939, 184

    1. B.S. Sumerlin; N.V. Tsarevsky; H. Gao; P. Golas; G. Louche; R.Y. Lee; K. Matyjaszewski, Click Functionalization of Well-Defined Copolymers Prepared by Atom Transfer Radical Polymerization, in ACS Symp. Ser. 2006, Vol. 944, 140

    Patents

    1. H. Gao*, K. Min, Hyperbranched Polymers and Synthesizing Hyperbranched Polymers with Uniform Structure in Confined Space, U.S. Pat. Appl. Publ. 2015, US 20150368379.

    2. Krzysztof Matyjaszewski; Halfeng Gao; James Spanswick, Preparation of Functional Star Macromolecules with Low Polydispersity, PCT Int. Appl. 2010, WO 2010111708.

    Outreach

    Equipment

    1 / 8
    Malvern Zetasizer with Auto-Titration
    2 / 8
    Shimadzu 2014 Gas Chromatography
    3 / 8
    THF GPC with Autosampler and Wyatt HELEOS II MALLS Detector
    4 / 8
    DMF GPC with Manual Injector and Waters 2414 RI Detector
    5 / 8
    Branson Sonicator/Cell Disruptor
    6 / 8
    Buchi Rotovap
    7 / 8
    Beckman Centrifuge
    8 / 8
    Hoods