Publications

Interested in Supporting Dr. Hyde's Research?

Selected Publications

Hyde, D.R. and Tu, C.P. (1982). Insertion sites and the terminal nucleotide sequences of the Tn4 transposon. Nucleic Acids Research 10: 3981-3993.

Hyde, D.R. and Tu, C.P.D. (1985). tnpM: A novel regulatory gene that enhances Tn21 transposition and suppresses cointegrate resolution. Cell 42: 629-638.

Palazzolo, M.J., Hyde, D.R., Raghavan, K.V., Mecklenburg, K.L., Benzer, S. and Meyerowitz, E.M. (1989). Use of a new strategy to isolate and characterize 436 Drosophila cDNA clones corresponding to RNAs detected in adult heads but not in early embryos. Neuron 3: 527-539.

Hyde, D.R., Mecklenburg, K.L., Pollock, J.A., Vihtelic, T.S. and Benzer, S. (1990). Twenty Drosophila visual system cDNA clones: One is a homolog of human arrestin. Proc. Natl. Acad. Sci. USA 87: 1008-1012.

Lee, Y.J., Dobbs, M.B., Verardi, M.L. and Hyde, D.R. (1990). dgq: A Drosophila gene encoding a visual system-specific Ga molecule. Neuron 5: 889-898.

Vihtelic, T.S., Hyde, D.R. and O'Tousa, J.E. (1991). Isolation and characterization of the Drosophila retinal degeneration B (rdgB) gene. Genetics 127: 761-768.

Vihtelic,T.S., M. Goebl, S. Milligan, J.E. O'Tousa and D.R. Hyde (1993) Localization of Drosophila retinal degeneration-B, a membrane-associated phosphatidylinositol transfer protein. J. Cell Biol. 122, No. 5:1013-1022.

Lee, Y.J., Shah, S., Suzuki, E., Zars, T., O'Day, P., and Hyde, D.R. (1994). The Drosophila dgq gene encodes a Ga protein that mediates phototransduction. Neuron 13: 1143-1157.

Shah, S. and Hyde, D.R. (1995). Two Drosophila genes that encode the alpha and beta subunits of soluble brain guanylyl cyclase. J. Biol. Chem. 270: 15368-15376.

Zars, T. and Hyde, D.R. (1996). rdgE: A novel retinal degeneration mutation in Drosophila. Genetics, 144: 127-138.

Chang, J.T., Milligan, S., Li, Y., Chew, C.E., Wiggs, J., Copeland, N.G., Jenkins, N.A., Campochiaro, P.A., Hyde, D.R., and Zack, D.J. (1997). Mammalian homolog of Drosophila retinal degeneration B rescues the mutant fly phenotype. J. Neurosci. 17: 5881-5890.

Milligan, S., Alb, J.G., Elagina, R., Bankaitis, V.A., and Hyde, D.R. (1997). The phosphatidylinositol transfer protein domain of Drosophila retinal degeneration B protein is essential for photoreceptor cell survival and recovery from light stimulation. J. Cell Biol. 139: 351-363.

Losey, G.S., Cronin, T., Goldsmith, T.H., Hyde, D.R., Marshall, N.J., and McFarland, W.N. (1999). The UV visual world of fishes: a review. J. Fish Biol. 54: 921-943.

Paetkau, D.W., Elagin, V.A., Sendi, L.M., and Hyde, D.R. (1999). Isolation and characterization of Drosophila retinal degeneration B suppressors. Genetics, 151: 713-724.

Vihtelic, T.S., C.J. Doro and D.R. Hyde (1999) Cloning and characterization of six zebrafish photoreceptor opsin cDNAs and immunolocalization of their corresponding proteins. Vis. Neurosci. 16: 571-585.

Lu, D., T.S. Vihtelic, D.R. Hyde, and T. Li (1999) A neuronal-specific mammalian homolog of the Drosophila retinal degeneration B gene with expression restricted to the retina and dentate gyrus. J. Neurosci. 19(17): 7317-7325.

Elagin, V.A., R.B. Elagina, C.J. Doro, T.S. Vihtelic, and D.R. Hyde (2000) Cloning and tissue localization of a novel zebrafish rdgB homolog that lacks a phospholipid transfer domain. Vis. Neurosci. 17: 303-311.

Vihtelic, T.S. and D.R Hyde (2000) Rod and cone photoreceptor cell death and regeneration in the intense-light-treated adult albino zebrafish (Danio rerio) retina. J. Neurobiology, 44: 289-307.

Kennedy, B.N., T.S. Vihtelic, L. Checkley, and D.R. Hyde (2001) Isolation of a zebrafish rod opsin promoter to generate a transgenic zebrafish line expressing EGFP in rod photoreceptors. J. Biol. Chem., 276: 14037-14043.

Vihtelic, T.S., Y. Yamamoto, M.T. Sweeney, W.R. Jeffery, and D.R. Hyde. (2001) Arrested differentiation and epithelial cell degeneration in zebrafish lens mutants. Dev. Dynam. 222: 625-636.

Vihtelic, T.S. and D.R. Hyde (2002) Zebrafish mutagenesis yields eye morphological mutants with retinal and lens defects. Vision Research, 42: 535-540.

Kosloff, M., Elia, N., Joel-Almagor, T., Timberg, R., Zars, T.D., Hyde, D.R., Minke, B., and Selinger, Z. (2003). Regulation of light-dependent Gqalpha translocation and morphological changes in fly photoreceptors. EMBO J. 22:459-468.

Iakhine, R., Chorna-Ornan, I., Zars, T., Elia, N., Cheng, Y., Selinger, Z., Minke, B., and Hyde, D.R. (2004). Novel dominant rhodopsin mutation triggers two mechanisms of retinal degeneration and photoreceptor desensitization. J. Neurosci. 24: 2516-2526.

Wei, X., Cheng, Y., Luo, Y., Shi, X., Nelson, S., and Hyde D.R. (2004). The zebrafish Pard3 ortholog is required for separation of the eye fields and retinal lamination. Dev. Biol. 269: 286-301.

Vihtelic, T.S., Y. Yamamoto, S.S. Springer, W.R. Jeffery, and D.R. Hyde (2005) Lens opacity and photoreceptor degeneration in the zebrafish lens opaque mutant. Dev. Dynam. 233(1): 52-65.

Shi, X., D.V. Bosenko, N.S. Zinkevich, S. Foley, D.R. Hyde, E.V. Semina, and T.S. Vihtelic (2005) Zebrafish pitx3 is necessary for normal lens and retinal development. Mech Dev, 122(4): 513-527.

Thummel, R., Burket, C.T., Brewer, J.L., Sarras, M.P., Li, L., Perry, M., McDermott, J.P., Sauer, B., Hyde, D.R., Godwin, A.R. (2005). Cre-mediated site-specific recombination in zebrafish embryos. Dev. Dyn. 233: 1366-1377.

Vihtelic, T.S., J.M. Fadool, J. Gao, K.A. Thornton, D.R. Hyde and G. Wistow (2005) Expressed sequence tag analysis of zebrafish eye tissues for NEIBank. Mol Vis, 11: 1083-100.

Thummel, R., Bai, S., Sarras, M.P., Song, P., McDermott, J., Brewer, J., Perry, M., Zhang, X., Hyde, D.R., and Godwin, A.R. (2006). Inhibition of zebrafish fin regeneration using in vivo electroporation of morpholinos against fgfr1 and msxb. Dev. Dyn. 235: 336-346.

Wei, X., Luo, Y., and Hyde, D.R. (2006). Molecular cloning of three zebrafish lin7 genes and their expression patterns in the retina. Exp. Eye Res. 82:122-131.

Vihtelic, T.S., J.E. Soverly, S.C. Kassen and D.R. Hyde (2006) Regional differences in photoreceptor cell death and regeneration in light-lesioned albino zebrafish Exp Eye Res, 82: 558-575.

Semina, E.V., Bosenko, D.V., Zenkevich, N.A., Soules, K.A., Hyde, D.R., Vihtelic, T.S., Willer, G.B., Gregg, R.G., and Link, B.A. (2006). Mutations in laminin alpha 1 result in complex, lens-independent ocular phenotypes in zebrafish. Dev. Bio. 299: 63-77.

Shi, X., Luo, Y., Howley, S., Dzialo, A., Foley, S., Hyde, D.R., and Vihtelic, T.S. (2006). Zebrafish foxe3: roles in lens morphogenesis through interaction with pitx3. Mech. Dev. 123: 761-782.

Thummel, R., Burket, C.T., and Hyde, D.R. (2006) Two different transgenes to study gene silencing and re-expression during zebrafish caudal fin and retinal regeneration. TSW Development & Embryology 1(S1), 65–81. DOI 10.1100/tswde.2006.275.

Thummel, R., M. Ju, L. Li, M. P. Sarras, Jr., and A. R. Godwin. (2007) Both Hoxc13 orthologs are functionally important for zebrafish tail fin regeneration. Dev Genes Evol. 2007. Apr 17.

Yu, C.J., Gao, Y., Willis, C.L., Li, P., Tiano, J.P., Nakamura, P.A., Hyde, D.R., and Li, L. (2007). Mitogen-associated protein kinase- and protein kinase A-dependent regulation of rhodopsin promoter expression in zebrafish rod photoreceptor cells. J Neurosci Res. 2007 Feb 15;85(3):488-96.

Tawk, M., Araya, C., Lyons, D., Bayley, P., Hyde, D.R., Tada, M., and Clarke, J. (2007). A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis. Nature. 446:797-800.

Fimbel, S.M., Montgomery, J.E., Burket, C.T., and Hyde, D.R. (2007). Regeneration of inner retinal layers after intravitreal injection of ouabain in zebrafish. J. Neurosci. 27:1712-1724.

Kassen, S.C., Ramanan, V., Montgomery, J.E., Burket, C.T., Liu, C.G., Vihtelic, T.S., and Hyde, D.R. (2007). Time course analysis of gene expression during light-induced photoreceptor cell death and regeneration in albino zebrafish. Dev Neurobiol. 2007 Jul;67(8):1009-31.

Alvarez, Y., Cederlund, M.L., Cottell, D.C., Bill, B.R., Ekker, S.C., Torres-Vázquez, J., Weinstein, B.M., Hyde, D.R., Vihtelic, T.S., and Kennedy, B.N. (2007). Genetic determinants of hyaloid and retinal vasculature in zebrafish. BMC Dev. Biol. 7(1):114.

Sherpa T, Fimbel, S.M., Mallory, D.E., Maaswinkel H., Spritzer, S.D., Sand, J.A., Li, L., Hyde, D.R., Stenkamp, D.L. (2008). Ganglion cell regeneration following whole-retina destruction in zebrafish. Dev Neurobiol. 2008 Feb 1;68(2):166-81.

Thummel, R., Kassen, S.C., Montgomery, J.E., Enright, J.M., Hyde, D.R. (2008) Inhibition of Müller glial cell division blocks regenration of the light-damaged zebrafish retina. Dev Neurobiol. 2008 Feb 15;68(3):392-408.

Yin, V.P., Thomson, J.M., Thummel, R., Hyde, D.R., Hammond, S.M., Poss, K.D. (2008) Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish. Genes Dev. 2008 Mar 15;22(6):700-5.

Burket, C.T., Montgomery, J.E., Thummel, R., Kassen, S.C., LaFave, M.C., Langenau, D.M., Zon, L.I., Hyde, D.R. (2008). Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters. Transgenic Res. 2008 Apr:17(2):265-79. Epub 2007 Oct 30.

Harding, R.L., Howley, S., Baker, L.J., Murphy, T.R., Archer, W.E., Winstow, G., Hyde, D.R., Vihtelic, T.S. (2008). Lengsin expression and function during zebrafish lens formation. Exp Eye Res. 2008 May;86(5):807-818. Epub 2008 Mar 2.

Hoptak-Solga, A.D., Nielsen, S., Jain, I., Thummel, R., Hyde, D.R., Iovine, M.K. (2008) Connexin43 (GJA1) is required in the population of dividing cells during fin regeneration. Dev Biol. 2008 May 15;317(2):541-8. Epub 2008 Mar 12.

Kassen, S.C., Thummel, R. Burket, C.T., Campchiaro, L.A., Harding, M.J., and Hyde, D.R. (2008). The Tg(cyclin B1:EGFP) transgenic zebrafish line labels proliferating cells during retinal development and regeneration. Mol. Vis 14:950-962.

Thummel R., Kassen S.C., Enright, J.M., Nelson, C.M., Montgomery, J. E., and Hyde, D.R. (2008). Characterization of Muller glia and neuronal progenitors in zebrafish adult retinal regeneration. Exp. Eye Res. 87: 433-444.

Calinescu, A.A., Vihtelic, T.S., Hyde, D.R., and Hitchcock, P.F. (2009). Cellular expression of midkine-a and midkine-b during retinal development and photoreceptor regeneration in zebrafish. J. Comp. Neurol. 514:1-10.

Kassen, S.C., Thummel, R. Campochiara, L.A., Harding, M.J., Bennet, N.A., and Hyde, D.R. (2009). CNTF induces photoreceptor neuroprotection and Muller glial cell proliferation through two different signaling pathways in the adult zebrafish retina. Exp. Eye Res. 88:1051-1064.

Yang, X., Zou, J., Hyde, D.R., Davidson, L., and Wei, X. (2009). Stepwise maturation of apicobasal polarity of the neuroepithelium is essential for vertebrate neurulation. J. Neurosci. 29: 11426 –11440.

Montgomery, J.E., Parsons, M.J., and Hyde, D.R. (2010). A novel model of retinal ablation demonstrates that the origin of regenerated rod photoreceptors is dependent on the extent of damage. J. Comp. Neurol. 518: 800-814.

Craig, S.E.L., Thummel, R., Ahmed, H., Vasta, G.R., Hyde, D.R., and Hitchcock, P.F. (2010). The zebrafish galectin Drgal1-L2 is expressed by proliferating Müller glia and photoreceptor progenitors and regulates the regeneration of rod photoreceptors. IOVS. 51: 3244-3252.

Thummel, R., Enright, J.M., Kassen, S.C., Montgomery, J.E., Bailey, T.J., and Hyde, D.R. (2010). Pax6a and Pax6b are required at different points in neuronal progenitor cell proliferation during zebrafish photoreceptor regeneration. Exp. Eye Res. 90: 572-582.

Ile, K.E., Kassen, S., Cao, C., Vihtelic, T., Shah, S.D., Mousley, C.J., Alb, J.G., Huijbregts, R.P.H., Stearns, G.W., Brockerhoff, S.E., Hyde, D.R. and Bankaitis, V.A. (2010). Zebrafish Class 1 Phosphatidylinositol Transfer Proteins: PITPβ and Double Cone Cell Outer Segment Integrity in Retina. Traffic. 11: 1151-1167.

Bailey, T.J., Fossum, S.L., Fimbel, S.M., Montgomery, J.E., and Hyde, D.R. (2010). The inhibitor of phagocytosis, O-phospho-L-serine, suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina. Exp. Eye Res. 91: 601-612.

Thomas, J.L., Vihtelic, T.S., DenDekker, A.D., Willer, G., Luo, X., Murphy, T.R., Gregg, R.G., Hyde, D.R., and Thummel, R. (2011). The loss of vacuolar protein sorting 11 (vps11) causes retinal pathogenesis in a vertebrate model of syndromic albinism. IOVS 52: 3119-3128.

Murphy, T.R., Vihtelic, T.S., Ile, K.E., Watson, C.T., Willer, G.B., Gregg, R.G., Bankaitis, V.A., and Hyde, D.R. (2011). Phosphatidylinositol synthase is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye. Exp. Eye Res. 93: 460-474. Cited in Faculty of 1000.

Qin, Z., Kidd, A.R., Thomas, J.L., Poss, K.D., Hyde, D.R., Raymond, P.A., and Thummel, R. (2011). FGF signaling regulates rod photoreceptor cell maintenance and regeneration in zebrafish. Exp. Eye Res. 93: 726-734.

Thummel, R. Bailey, T.J., and Hyde, D.R. (2011) In vivo electroporation of morpholinos into the adult zebrafish retina. J. Vis. Exp. 58, e3603. DOI: 10.3791/3603 (2011).

Hyde, D.R., Goodwin, A.R., and Thummel, R. In vivo electroporation of morpholinos into the regenerating adult zebrafish tail fin. J. Vis. Exp. in press.

Tu, C.P., Timmerman, K.P., and Hyde, D.R. (1982). Specificity of Tn3 and Tn4 Transposition. in Genetic Engineering Techniques, Huang, P.C., Kuo, F.T., and Wu, R. eds. (New York: Academic Press), pp. 203-224.

Forte, M., Quan, F., Hyde, D., and Wolfgang, W. (1993). Ga Proteins in Drosophila: Structure and Developmental Expression. in GTPases in Biology II: a Handbook of Experimental Pharmacology, volume 108. Dickey, B.F. and Birnbaumer, L., eds. (New York: Springer-Verlag), pp. 319-334.

Hyde, D.R., Milligan, S., and Vihtelic, T.S. (1995). The Role of the Retinal Degeneration B Protein in the Drosophila Visual System. in Degenerative Diseases of the Retina, Proceedings of the Sixth International Symposium on Retinal Degenerations. Anderson, R.E., LaVail, M.M., and Hollyfield, J.G., eds. (New York: Plenum Press), pp. 243-254.

Hyde, D.R., Milligan, S., and Zars, T. (1997). Rhodopsin-Dependent Models of Drosophila Photoreceptor Degeneration. in Degenerative Retinal Diseases, Proceedings of the Seventh International Symposium on Retinal Degenerations. M.M. LaVail, J.G. Hollyfield and R.E. Anderson, eds. (New York: Plenum Press), pp. 145-158.