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Albert Libchaber
The Center for Studies in Physics and Biology
The Rockefeller University


Towards and Artificial Cell

We show first how a temperature gradient can lead to giant DNA accumulation by thermophoresis and to DNA sequence amplification in a convection set-up.  Non-equilibrium thermodynamics can thus help to solve some nagging problems of critical concentration and sequence selection in a prebiotic soup.

Secondly, we show that a vesicle bioreactor can function for many days in an homeostatic state producing proteins.  This is a first necessary step to artificial cells.  The next step will be vesicle replication.


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