Alan S. Perelson
Theoretical Division
Los Alamos National Laboratory


New Developments in Modeling the Dynamics of Viral Infections

I will present a general overview of the problem of modeling viral infections in vivo. The point of view that I will take is that models should be useful for giving insights into the treatment of human disease. From this perspective, I will discuss two examples: HIV infection and hepatitis C virus (HCV) infection. I will show how viral dynamic models can provide insights into both the basic biological processes underlyling infection as well as treatment with drug or vaccine. I will also discuss aspects of the immune response to these infections.