Workshop on Interdisciplinary Biomedical Research
Center for the Study of Biocomplexity (ICSB), University of Notre Dame, USA
Department of Applied and Computational Mathematics and Statistics (ACMS), University of Notre Dame, USA
Centre for Mathematical Biology (CMB), University of Oxford, UK
Oxford Centre for Collaborative Applied Mathematics (OCCAM), University of Oxford, UK
Sponsored by the Rev. Julius A. Nieuwland Lecture Series, College of Science, University of Notre Dame, USA
Sponsored by the College of Engineering, University of Notre Dame, USA

July 18th - 19th, 2011
(Monday - Tuesday)

Location: University of Notre Dame London Centre
http://www.nd.edu/~ndlondon/londoncentre/londoncentre.html

LondonCentre

REGISTRATION

WORKSHOP PARTICIPANTS

PHOTOGRAPHIC TOUR OF THE LONDON CENTRE

LODGING INFORMATION

WORKSHOP POSTER (PDF)

SCHEDULE OF EVENTS (PDF)


Organizers:
Mark Alber (University of Notre Dame), malber@nd.edu;
Philip Maini (University of Oxford),
maini@maths.ox.ac.uk;
Glen Niebur (University of Notre Dame),
gniebur@nd.edu;


New insights into emergent organizational properties of many biological phenomena can be gained by, and indeed require, mathematical and computational modeling.  Such modeling does not replace analysis at the cellular and molecular levels but complements it.  Mathematical and computational analysis is the best means available for describing and understanding the spatiotemporal behaviors of systems containing many components and operating on multiple scales.  Complex biomedical modeling efforts include predictive multiscale simulations consisting of different submodels at each scale, scalable parallelism for heterogeneous dynamical simulations, a data-rich environment with experimentally determined model parameters, and, finally, distributed multidisciplinary research teams and resources.

The goal of the Workshop is to bring together researchers in biomedical engineering and mathematical and computational biology from the US and UK to discuss recent developments in biomedical modeling and experiments, as well as possible future collaborations.  The two main biomedical topics of the Workshop will be biomechanics, including adaption or response of tissues to mechanical, chemical, or electromagnetic stimuli, and thrombus formation.

Summaries of all Workshop presentations and posters will be compiled into a booklet to be provided to all participants. These will also be made available electronically on the ICSB website.  Participants of the Workshop will be invited to contribute to the special issue of the Bulletin of Mathematical Biology (Springer).


WORKSHOP SCHEDULE

Monday, July 18th, 2011

8:15  – 8:45  a.m. Registration and Coffee
8:45 – 9:00 a.m.

Opening Remarks

9:00 – 9:45 a.m. Dr. Nicolas Smith, Head of the Department of Biomedical Engineering, King’s College London:  “Multi-scale Modelling at the Heart of the Clinic”
9:45 – 10:30 a.m. Dr. Arezoo Ardekani, Department of Aerospace and Mechanical Engineering, University of Notre Dame:  “Low Reynolds Number Swimming in Stratified Fluids”
10:30 – 10:45 a.m. Coffee Break
10:45 – 11:30 a.m. Dr. C. Ross Ethier, Head of the Department of Bioengineering, Imperial College London: “Combined Numerical and Experimental Studies of Optic Nerve Head Biomechanics in Glaucoma”
11:30 – 1:30 p.m. Lunch
1:30 – 2:15 p.m. Dr. Roeland Merks, Netherlands Institute for Systems Biology (NISB) and Centrum Wiskunde & Informatica (CWI):  “Cell-based Computational Modeling of Collective Cell Behavior and Cell-ECM Interactions During Angiogenesis”
2:15 – 3:00 p.m. Dr. Sarah Waters, Mathematical Institute, University of Oxford:  “Mathematical Modelling of Tissue Engineering”
3:00 – 3:15 p.m. Coffee Break
3:15 – 4:00 p.m. Dr. Gwendolen Reilly, Department of Materials Science and Engineering, The University of Sheffield:  “Mechanobiology of Bone Tissue Engineering”
4:00 – 4:45 p.m. Dr. Philipp Thurner, School of Engineering Sciences, University of Southampton:  “Interfaces and Structural Hierarchy in Bone-Determinants Of Mechanical Competence"
4:45 – 5:00 p.m. Coffee Break
5:00 – 5:45 p.m. Dr. Jeremy Gunawardena, Department of Systems Biology, Harvard Medical School:  “A Linear Framework for Nonlinear Biochemical Systems"
5:45 – 6:00 p.m. Break
6:00 – 7:30 p.m. Reception

 

Tuesday, July 19th, 2011

8:15 – 9:00 a.m. Registration and Coffee
9:00 – 9:45 a.m. Dr. Alain Goriely, Director of the Oxford Centre for Collaborative Applied Mathematics (OCCAM), Mathematical Institute, University of Oxford:  “The Role of Residual Stress in Biological Tissues:  History, Geometry, and Applications”
9:45 – 10:30 a.m. Dr. Aaron Fogelson, Department of Mathematics, University of Utah:  “Mathematical Modeling of Blood Clotting:  The Interplay of Coagulation Chemistry, Platelet Deposition, and Flow”
10:30 – 10:45 a.m. Coffee Break
10:45 – 11:30 a.m. Dr. Alexander Panfilov, Department of Physics and Astronomy, Ghent University:  “Anatomical Modelling of Electrical and Mechanical Function of the Heart”
11:30 – 1:30 p.m. Lunch
1:30 – 1:50 p.m. Dr. Jasmina Panovska-Griffiths, Department of Medical Physics and Bioengineering, University College London:  “Gene Regulatory Logic for Vertebrate Neural Tube Patterning”
1:50 – 2:25 p.m. Dr. Chris Rhodes, Department of Infectious Diseases and Institute for Mathematical Sciences, Imperial College London:  “Eco-epidemiological Models and Data Assimilation”
2:25 – 3:00 p.m. Dr. Paul Parham, The Grantham Institute for Climate Change, Imperial College London:  “Modelling the Impacts of Climate Change on Infectious Disease Dynamics”
3:00 – 3:15 p.m. Coffee Break
3:15 – 4:00 p.m. Dr. Sandra Shefelbine, Department of Bioengineering, Imperial College London:  “Modelling and Simulating Bone Adaptation to Loading”
4:00 – 4:45 p.m. Dr. Mark Thompson, Department of Engineering Science, University of Oxford:  “Models for Tendon Mechanobiology”
4:45 – 5:30 p.m. Dr. Diane Wagner, Department of Aerospace and Mechanical Engineering, University of Notre Dame:  “Modeling the Interface Between Native and Engineered Cartilage”

 

For additional information, please contact: Kassie.Spencer@nd.edu or malber@nd.edu.

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Last Updated: Friday, July 15, 2011
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