I am a fifth year graduate student interested in applying my chemical engineering background to conduct translational research in biology and health. My current research focus is to develop a high-content cell-based screening assay. I will apply this method to identify the biological function of novel therapeutics for breast cancer brain metastases. This approach will dramatically increase the speed and accuracy of pre-clinical functional validation of compounds for brain metastasis.
I use Drosophila to study the impact of mechanical forces on cellular processes and organogenesis. Currently I am working on developing novel microfluidic strategies to manipulate Drosophila organs under live observation on a confocal microscope.
I am elucidating the genetic and mechanical mechanisms behind the regulation of tissue size in the Drosophila embryonic epidermis. Currently, I am studying cellular and biochemical readouts of embryos with perturbations in cell cycle, cell death, and signaling pathway activity.
My research focuses on calcium signaling in developing epithelial tissues in Drosophila. Currently, I am using the wing imaginal discs as the model organ for investigating the interplay between intercellular calcium signaling and various morphogen pathways (hedgehog, wingless, notch etc.).