We use a combination of experimental and computational approaches to study pattern formation, growth control, and regeneration in order to inspire new ways to treat human diseases, such as cancer, and to accelerate wound healing and regeneration.
Lab openings: Interested undergraduates and potential graduates and post-doctoral researchers are welcome to inquire about available positions in the lab. Please note that undergraduate research positions require a 15 hour per week commitment to the research project.
April 8, 2017: We are co-organizing the 5th Midwest Q-Bio Symposium @ University of Notre Dame. It looks like it will be a great turnout!
March 2017: Contratulations to Paulina Eberts for her National Science Foundation Gradute Fellowship award!
Paulina was selected as an undergraduate student in chemical engineering. Her thesis is "Extension of Non-destructive 3D Immunostaining to Paraffin Embedded Tissues."
November 2016: Our collaborative work is now published in Interface! Robust cell tracking in epithelial tissues through identification of maximum common subgraphs. Congratulations especially to lead author Jochen Kursawe.
November 2016: We welcome two new members to the lab: Jamison Jangula and Dharsan Soundarrajan.
July 2016: Congratulations to Pavel! He was selected as an Walther Cancer Foundation Interdisciplinary Interface Training Project (IITP) fellow through the Harper Cancer Research Institute.
June 7, 2016: Congratulations, Dr. Miranda Burnette! Great job on your dissertation defense. Way to go!
May 2016: Megan, welcome to the lab! Megan Levis joins the group.
March 1 2016: We have been awarded an NSF CAREER award for our project, "Integrative Analysis for Reverse Engineering Embryonic Pattern Repair Mechanisms."
March 1 2016: In collaboration with the Hoelzle and Zhang labs, a short communication describing on-chip 3D tissue histology for microbiopsies is now online in Biomicrofluidics. Great work team! Links to the press release is found here.
February 26, 2016: Congratulations to Qinfeng Wu for passing his Ph.D. Candidacy exam. Way to go!
A collaborative study with the Fletcher and Baker groups on the capabilities and limitations of tissue size control through passive mechanical forces is now in press in PLOS Computational Biology!
Our study examining the spatiotemporal dynamics of calcium flashes due to local wounding is now online.
July 2015: Congratulations to Cody Narciso, who was named a 2015/16 Berry Family Foundation Graduate Fellowships in Advanced Diagnostics & Therapeutics. See more at here.
From the CBE Website: "Qinfeng Wu, a graduate student in the Department of Chemical and Biomolecular Engineering, was one of the 2015 winners in the annual Research Like a Champion competition. Sponsored by the Harper Cancer Research Institute, the competition is open to individual students/student groups across all disciplines of the University. Participants submit innovative approaches to the fight against cancer. The submitted proposals address causes, treatment, or prevention of the disease.
Wu’s winning project, “Cell Competition in Breast Cancer: Functional Identification of Genes that Determine Whether Breast Cancer Cells Out-compete Breast Epithelial Cells,” focuses on how breast cancer cells avoid tumor suppression treatments and beat out normal cells for nutrients, as well as how best to identify and change the mechanisms through which this cell competition occurs."
April 2015: Congratulations to the start-up Enlightened Diagnostics, Inc. on their achievements at the McCloskey Business Plan competition and at the Rice Business Plan Competition. For a description of their success, click here.
February 2015: Congratulations to the Englightened Diagnostics team on their victory at the Cardinal Challenge business plan competition! The team is presenting on a novel 3-D imaging platform developed iin collaboration with the Hoelzle and Zhang labs to improve the amount of information available for clinicians from biopsies.
January 2015: Cody passed his Candidacy exam. Congratulations!
July 2014: Miranda publishes her chemically defined medium for long-term maintenance and growth of Drosophila cells. The first truly chemically defined medium for Drosophila cell culture. In addition, the paper highlights a strategy for rationale media design. Congratulations!
April 15, 2014: Cody Narciso and Kyle Cowdrick (Mentor: Siyuan Zhang) win the Harper Cancer Research Institute's "Research Like A Champion" Award. Congratulations!
January 30, 2014: Miranda passes her Candidacy exam. Congratulations!
December 12, 2013: Lab Christmas party. Merry Christmas and Happy New Year!
Pavel Brodskiy and Qinfeng (Austin) Wu officially join the group. Welcome!
June 11, 2013: Jessica Freeman selected as a HCRI Summer Undergraduate Research Fellow. Congratulations Jessica!
March 4, 2013: Cody Narciso presented at the Workshop on Physical Approaches to Studying the Cytoskeleton and Cell Motility: https://www3.nd.edu/~icsb/Workshop_2013/.
January 12-16, 2013: Miranda presented a poster at SLAS 2013: Miranda Burnette, Jonathan Chen, and Jeremiah Zartman, Combinatorial Inverse Drug Screen Pipeline to Probe Epithelial Wound Healing in a Model Genetic Organ Culture System. SLAS 2013. January 12-16, 2013.
October 2012: Cody Narciso joins the lab. Welcome!
March 2012: Teresa Brito-Robinson joins the lab. Welcome!
January 2012: Lab officially opens. Miranda Burnette joins the lab. Welcome!
Christmas dinner with the lab group - December 6, 2012 at J.W. Chen's.
Lab Picnic -- scheduled for May 2013. Details to follow.