Growth control of epithelial tissues

Growth control of epithelial tissues

Understanding how individual cells and whole organs regulate their size is essential to developing new techniques in treating cancer. What is lacking is a quantitative understanding of how cells incorporate external inputs from their surroundings to regulate final tissue size. Our lab employs live imaging using confocal microscopy, quantitative data analysis and modeling to further our understanding the regulatory network determining robust growth control. The image to the left is a genetically modified wing, showing an overgrowth phenotype.