University of Notre Dame

Marvin J. Miller

Dr. Miller is currently a George and Winifred Clark professor at the University of Notre Dame. He is also the Program Director of the Notre Dame Chemistry-Biology-Biochemistry-Interface (CBBI) Training Program.



Contact Information

251 Nieuwland Science Hall
Department of Chemistry and Biochemistry
University of Notre Dame
Notre Dame, IN 46556
Phone & Fax:
Tel. 574-631-7571
Fax 574-631-6652

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Professional Information


  • 1971 B.S. in Chemistry, North Dakota State University
  • 1976 Ph.D. in Bioorganic Chemistry, Cornell University (G. M. Loudon)
  • 1975-1977 NIH Postdoctoral Fellow, Univeristy of California-Berkeley (Henry Rapoport)


  • 1977-1982 Assistant Professor of Chemistry, University of Notre Dame
  • 1982-1986 Associate Professor of Chemistry, University of Notre Dame
  • 1986-1996 Professor of Chemistry & Biochemistry, University of Notre Dame
  • 1996-present George and Winifred Clark Professor, University of Notre Dame
  • 2003-2005 Chairman, Department of Chemistry and Biochemistry, University of Notre Dame
  • 2007-present Program Director, Chemistry-Biology-Biochemistry-Interface (CBBI) Training Program, University of Notre Dame

Selected Awards and Honors:

  • 1981-1985 Alfred P. Sloan Foundation Fellow
  • 1983-1988 NIH Research Career Development Award
  • 1983 Award for Outstanding Research (Notre Dame Chapter of Sigma Xi)
  • 1988 Visiting Fellow at the Australian National University
  • 1994 Schilts/Leonard Teaching Award
  • 2002 Kaneb Teaching Award


  • 1991-1995 Editorial Advisory Board, Journal of Organic Chemistry
  • 1999-present Editorial Board for Organic Synthesis
  • 1999-present Editorial Advisory Board, BioMetals
  • 1999 Editor for Tetrahedron Symposium-in-Print
  • 2000-present Editorial Board, Journal of Antibiotics
  • 2000-present Editorial Board, Current Medicinal Chemistry-Infectious Diseases
  • 2001-present COBRE Advisory Board, North Dakota State University

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Research Overview

Research Interests:

Dr. Miller's research program is internationally recognized as a leader in the design, synthesis and study of new antibiotics, especially beta- lactams, siderophores (microbial iron chelators) and conjugates. His research is centered on the development of new methodology and its incorporation into the synthesis and study of biologically important compounds. Special emphasis is given to asymmetric syntheses and studies of hydroxamic acid containing microbial iron transport agents (siderophores), amino acids, peptides, beta-lactam antibiotics, novel antifungal agents, potential antimalarial agents, carbocyclic analogs of antifungal and anticancer nucleosides and MRI (Magnetic Resonance Imaging) contrast agents. Development and applicatrion of new synthetic methodolody is an important part of the Miller group reserach program. Recently emphasis has included studies of acynitroso cycloaddition for asymmetric syntheses of a variety of biologically interesting compounds that targets several important therapeutic areas. For a more detailed description of Miller group research, please visit the Research webpage.

Over 200 peer-reviewed publications and patents. For a full listing of publications and patents, please visit the Publications wepage.
Dr. Miller has supervised over 60 students in their thesis or dissertation research and over 40 postdoctoral researchers during his tenure at the University of Notre Dame. For more information on current group members, please visit the Current Miller Group Members webpage, and for a listing of former miller group members, please visit the Former Miller Group Members wepage.

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Last updated on 2008-09-18