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UNDERGRADUATE RESEARCH POSITION
"DESIGN OF A MUSEUM EXHIBIT ON CARDIOVASCULAR PHYSIOLOGY AND PATHOLOGY"
 
Healthworks! flow loop

Project background: The MSCBL has partnered with HealthWorks! Kids’ Museum to educate children on the engineering, scientific and clinical aspects of the cardiovascular system in the context of an interactive activity on the human circulation. Over the past two years, undergraduate students in the MSCBL have designed and fabricated an interactive and simplified representation of the human circulation enabling flow visualization through the different components.

Project objective : the next step of the project is to improve the design of the prototype exhibit and to complement the existing interactive modules with new modules (e.g., emboli, gas exchange in lungs).

  • Qualifications:
    Major in Aerospace or Mechanical Engineering or Computer Science and Engineering. Previous research experience and commitment for two-semester appointment preferred. Previous experience with CAD design preferred.

    Project period: fall 2013, spring 2014, summer 2014

  • UNDERGRADUATE RESEARCH POSITION
    "DESIGN OF LABORATORY MODELS OF CALCIFIED VALVES FOR USE WITH PARTICLE-IMAGE VELOCIMETRY"
     
    Injected leaflet
     
    3D reconstruction using micro-CT

    Project background: The flow through heart valves has been extensively characterized in vitro using polymeric, bioprosthetic, mechanical and more recently tissue valves. In contrast, flow studies in diseased (i.e., calcified) heart valves are few. Capturing the flow through calcified valves under different flow regimes (physiologic, hypertensive) would provide new insights into the impact of valvular disease on valvular performance and function. The purpose of this study is to develop anatomically realistic calcified aortic valve models for use with particle-image velocimetry.

    Project objectives:
    - objective 1:
    to develop an experimental protocol based on hydroxyapatite injection to generate calcific lesions of different sizes in native porcine leaflets.
    - objective 2: to assess mechanically the calcified valve models and validate the injection protocol in terms of repeatability using micro-CT imaging.

  • Qualifications:
    Major in Aerospace or Mechanical Engineering or Computer Science and Engineering. Previous research experience and commitment for two-semester appointment preferred.

    Project period: fall 2013, spring 2014, summer 2014