The Multi-Scale Cardiovascular Bioengineering Laboratory (MSCBL) at Notre Dame was established in August 2008 by Dr. Philippe Sucosky in the Department of Aerospace and Mechanical Engineering. The MSCBL is located in the Multidisciplinary Research Building and is part of the Bioengineering Graduate Program.
1- understand the complications caused by congenital and degenerative cardiovascular disorders
2- optimize the tissue engineering of functional heart valve substitutes
3- predict cardiovascular tissue remodeling and disease progression from a fluid mechanical perspective.
In this highly interactive research program, the knowledge of the flow characteristics in different cardiovascular disorder configurations and the identification and prediction of the mechanobiological pathways leading to those disorders will guide the development of early medical interventions for the treatment of cardiovascular pathologies.