Core Manager, Anatomic Pathology
Associate Professional Specialist
University of Notre Dame
HT, Hartford Hospital, School of Allied Health, CT, 1987
W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall
University of Notre Dame
Notre Dame, IN 46556
Phone: (574) 631-2318
Fax (574) 631-4048
Honors and Awards
1983 Trinity College of Vermont, Tri Beta Honor Society
1987 American Society of Clinical Pathologists, H.T. Certification
1987 Hartford Hospital, School of Allied Health, Highest Achievement Award
Areas of Focus
Ms. Sandoval-Cooper is responsible for direction in the histology facility. In that role, development of specialized stains, training of personnel, supervising operations, and organizing and executing project priorities, are major areas of concentration.
Selected Recent Publications
Xu H, Noria F, Sandoval-Cooper MJ, Menchen H, Donahue DL, Ploplis VA, Castellino FJ. (2009) Severe deficiency of coagulation Factor VII results in spontaneous cardiac fibrosis in mice. J Pathol. 217:362-371.
Iwaki T, Sandoval-Cooper MJ, Tenenhouse HS, Castellino FJ. (2008) A missense mutation in the sodium phosphate co-transporter S1c34a1 impairs phosphate homeostasis. J Am Soc Nephrol. 19:1753-1762.
Castelllino FJ, Ganopolsky JG, Noria F, Sandoval-Cooper MJ, Ploplis VA. (2006). Focal arterial inflammation is augmented in mice with a deficiency of the protein C gene. Thromb Haemost. 96:794-801.
Iwaki T, Sandoval-Cooper MJ, Brechmann M, Ploplis VA, Castellino FJ (2006). A fibrinogen deficiency accelerates the initiation of LDL-cholesterol-driven atherosclerosis via thrombin generation and platelet activation in genetically-predisposed mice. Blood. 107:3883-3891.
Ploplis VA, Balsara R, Sandoval-Cooper MJ, Yin ZJ, Batten J, Modi, N, Gaduoa D, Donahue DL, Martin JA, Castellino FJ. (2004). Enhanced in vitro proliferation of aortic endothelial cells from PAI-1-/- mice. J Biol Chem. 279:6143-6151.
Castellino FJ, Liang Z, Volkir SP, Haalboom E, Martin JA, Sandoval-Cooper MJ, Rosen ED. (2002). Mice with a severe deficiency of the endothelial protein C receptor gene develop, survive, and reproduce normally, and do not present with enhanced arterial thrombosis after challenge. Thromb Haemost. 88:462-472.
Iwaki T, Sandoval-Cooper MJ, Paiva M, Kobayashi T, Ploplis VA, Castellino FJ. (2002).
Fibrinogen stabilizes placental-maternal attachment during embryonic development in the mouse. Am J Pathol. 160:1021-1023.