Protein Structure Prediction
Secondary structure
a) Chou-Fasman method
Frequency at which a given aa occurs in an a helix in a set of protein structures = fa = na/n, where na = number of amino acid residues of the given type that occur in a helices, and n = total number of residues of this type in the protein set
Propensity of a particular aa residue to occur in an a helix =
Pa = fa/
20 residues
Pa > 1: residue occurs with greater than average frequency
in an a helix
Also applies to b-structure
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