Table of Contents
The adult brain after stroke: Neuronal replacement from endogenous precursors
Overview
Background
Background: Magavi et al.
Background: Magavi et al.
Approaching clinical relevancy
Methods: MCAO
Methods: Markers of proliferation
Methods: Markers of neurogenesis
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Stroke leads to neurogenesis in damaged striatum
Stroke leads to neurogenesis in damaged striatum
Evidence for self-repair following stroke
Proliferation and recruitment of neuroblasts
Proliferation and recruitment of neuroblasts
Methods: Markers of neurogenesis
Proliferation and recruitment of neuroblasts
Evidence for self-repair following stroke
Neurons migrate from SVZ to lesion
Morphologies of migrating neurons
Evidence for self-repair following stroke
Cells express markers of striatal medium spiny neurons
Markers of developing striatal neurons
Results: developmental markers
Evidence for self-repair following stroke
Neurogenesis and maturation
Evidence for self-repair following stroke
Summary
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