Christopher Austin, M.D.on NIH's Molecular Libraries Network

November 6, 2009 - Christopher Austin, M.D., Director of the NIH Chemical Genomics Center (NCGC) at the National Human Genome Research Institute (NHGRI), NIH.

Dr. Christopher Austin discussed his work at NCGC, particularly his involvement with the Molecular Libraries Probe Production Centers Network (MLPCN). MLPCN is a network of small molecule screening centers, which perform High Throughput Screening for public sector researchers against over 300,000 chemically diverse small molecules. MLPCN's activities, including information about small molecules, which can be used as “chemical probes” to study genes and signaling pathways, will be made available through PubChem to public and private sectors.

Bringing NIH's capacity for large-scale screening to the early stages of identifying chemicals, which modulate biological functions and assisting researchers with drug target validation, promises to make drug discovery for rare and neglected diseases economically viable. Dr. Austin's lecture, "Therapeutics for Rare and Neglected Diseases Program" discussed the evolution of small molecule screening at NIH. Below: Dr. Austin and Dr. Haldar in class.




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