Publication List Olaf Wiest



1.             A. Gieseler, E. Steckhan, O. Wiest: “Photoinduced Electron-Transfer-Catalyzed Diels-Alder-Reaktion between Indole and 1,3-Cyclohexadienes” Synlett 1990, 275-277.

2.             A. Gieseler, E. Steckhan, O.Wiest, F. Knoch: “Photochemically Induced Radical Cation Diels-Alder Reaction of Indole and Electron-Rich DienesJ. Org. Chem. 1991, 56, 1405-1411.

3.             O.Wiest, E. Steckhan, F. Grein: “Selectivity in Radical-Cation Diels-Alder Reactions of Indole and Electron-Rich Dienes: A Semiempirical Approach” J. Org. Chem. 1992, 57, 4034-4037.

4.             O. Wiest, E. Steckhan: “Electron Transfer Catalyzed Diels-Alder-Reactions with 2-Vinylindoles” Angew. Chem. 1993, 105, 932-934; Angew. Chem. Int. Ed. Engl. 1993, 32, 901-903.

5.             O. Wiest, E. Steckhan: “Radical Cation Diels-Alder Reaction of Indoles and Exocyclic DienesTetrahedron Lett. 1993, 34, 6391-6394.

6.             O. Wiest, A. Gieseler, E. Steckhan: “ Synthesis of (-)-(1S,2R,4R)-4,9-diacetyl-2-isopropyl-1,2,3,4-tetrahydrocarbazol-1-aldehyde” in: Photochemical Key Steps in Organic Synthesis (Ed.: A.G. Griesbeck, J. Mattay), VCH Weinheim 1994 pp. 259-262.

7.             O. Wiest, K.N. Houk: “Condensation and Commentary on: Crystal structures of the monofunctional chorismate mutase from Bacillus subtilis and its complex with a transition state analog (Y.M. Chook, H. Ke and W.N. Lipscomb Proc. Natl. Acad. Sci. USA 1993, 90, 8600)” Chemtracts  1994, 7, 45-48.

8.             O. Wiest, K.A. Black, K.N. Houk: “Density Functional Theory Isotope Effects and Activation Energies for the Cope and Claisen Rearrangements”, J. Am. Chem. Soc. 1994, 116, 10336-10337.

9.             O. Wiest, K.N. Houk; “On the Transition State of the Chorismate-Prephenate Rearrangement”, J. Org. Chem. 1994, 59, 7582-7584

10.         O. Wiest, K.N. Houk, K.A. Black, B.E. Thomas IV: “Secondary Kinetic Isotope Effects of Diastereotopic Protons in Pericyclic Reactions. A New Mechanistic Probe” J. Am. Chem. Soc. 1995, 117,  8594-8599.

11.         O. Wiest, K.N.Houk: “Stabilization of the Transition State of the Chorismate-Prephenate Rearrangement: An ab initio Study of Enzyme- and Antibody Catalysis” J. Am. Chem. Soc. 1995, 117, 11628-11639.



12.         O. Wiest: “DFT Studies of the Methanol Radical Cation HypersurfaceJ. Mol. Struct. (THEOCHEM)  1996, 368, 39-48.

13.         O. Wiest, K. N Houk: “Density Functional Theory Calculations of Pericyclic Reaction Transition Structures” Top. Curr. Chem. 1996, 183, 1-24.

14.         O. Wiest, D. C. Montiel, K. N. Houk: “Quantum Mechanical Methods and the Elucidation of Pericyclic Reaction Mechanisms: Interpretations and Predictions” J. Phys. Chem. A 1997, 101, 8377-8388. 

15.         K.N. Houk, M. Nendel, O. Wiest, J. Storer: “The Vinylcyclopropane-Cyclopentene Rearrangement: A Prototype Thermal Rearrangement Involving Competing Diradical Concerted and Stepwise Mechanisms” J. Am. Chem. Soc. 1997, 119, 10545-10546.

16.         O. Wiest: “Ab Initio Studies of Ring Opening of the Cyclobutene Radical CationJ. Am. Chem. Soc. 1997, 119, 7513-7519.

17.         O. Wiest, A. J. Largoza: “Electrostatic Potential Surfaces for the Thymine Dimer and It's Radical Ions: Insights into Binding and Catalysis” Internet J. Sci.-Biol. Chem. 1997, 1 (electronic publication).

18.         P. Kast, Y. B. Terawi, O. Wiest D. Hilvert, K. N. Houk, R. N. Goldberg: “Thermodynamics of the Conversion of Chorismate to Prephenate: Experimental Results and Theoretical Predictions.” J. Phys. Chem. B, 1997, 101, 10976-10982.

19.         K. Kawamura, M. Shang, O. Wiest, T. P. Fehlner: “Synthesis and Structure of {h5-C5H5Cr}2{m-h6:h6-(m-1,2-C3H6-1,2-C2B4H4)}. An Unusual 24 Electron Triple-Decker Sandwich Complex Containing a Metal-Stabilized, Planar TetraborobenzeneInorganic Chemistry 1998, 37, 608-609.

20.         J. Amaudrut, D. J. Pasto, O. Wiest: “Theoretical Studies of the Sulfenate-Sulfoxide Rearrangement” J. Org. Chem. 1998, 63, 6061-6064.

21.         O. Wiest: “Ab Initio Calculations of Organic Transition Structures” In: The Encyclopedia of Computational Chemistry, Vol. 5” P. v. R. Schleyer; N. L. Allinger, T. Clark, J. Gasteiger, P. A. Kollman, H. F. Schaefer III, P. R. Schreiner. (Eds.); John Wiley & Sons: Chichester, 1998, 3104-3114.

22.         D. J. Gustin, P. Mattei, P. Kast, O. Wiest, L. Lee, W. W. Cleland, D. Hilvert: “Heavy atom isotope effects reveal a highly dissociative transition state for chorismate mutaseJ. Am. Chem. Soc. 1999, 121, 1756-1757.

23.         D. B. Sanders, O. Wiest: “A Model of the Enzyme-Substrate Complex of DNA Photolyase and Photodamaged DNA.” J. Am. Chem. Soc. 1999, 121, 5127-5134.

24.         G. D. Reddy; O. Wiest, T. Hudlicky, V. Schapiro, D. Gonzales: “Electron Transfer Catalyzed [2+2] Cycloreversion of Benzene DimersJ. Org. Chem. 1999, 64, 2860-2863.

25.         U. Haberl, E. Steckhan, O. Wiest: “Theoretical Studies of the Radical Cation Diels-Alder Reaction” J. Am. Chem. Soc. 1999, 121, 6730-6736.

26.         U. Haberl, E. Steckhan, O. Wiest, S. Blechert: “Electron Transfer Catalyzed Diels-Alder Reactions of Vinylindoles with Exocyclic DienesChemistry - Europ. J.1999, 5, 2859-2865.

27.         O. Wiest: “On the Structure and [2+2] Cycloreversion of the Cyclobutane Radical CationJ. Phys. Chem. A 1999 103, 7907-7911.

28.         J. Oxgaard, O. Wiest: ”The Vinylcyclopropane Radical Cation Rearrangement and Related Reactions on the C5H8•+ HypersurfaceJ. Am. Chem. Soc. 1999, 121, 11531-11537.

29.         D. A. Plattner, D. Feichtinger, J. El-Bahraoui, O. Wiest: “Coordination Chemistry of Manganese-Salen Complexes Studied by Electrospray Tandem Mass Spectrometry: The Significance of Axial LigandsIntl. J. Mass. Spectrom. 2000, 195, 351-362.

30.         M. Nendel, D. Sperling, O. Wiest, K. N. Houk: “Computational Explorations of Vinylcyclopropane-Cyclopentene Rearrangements and Competing Diradical StereoisomerizationsJ. Org. Chem. 2000, 65, 3259-3268.

31.         N. J. Saettel, O. Wiest: “[1,5]-H Shifts: Pentadienes and Beyond” J. Org. Chem. 2000, 65, 2331-2336.

32.         J. Amaudrut, O. Wiest: “The Thermal Sulfenate-Sulfoxide Rearrangement: A Radical Pair Mechanism” J. Am. Chem. Soc. 2000, 122, 3367-3374.

33.         J. Amaudrut, O. Wiest: “Epoxide Formation by Ring Closure of the Cinnamyloxy Radical” Org. Lett. 2000, 2, 1251-1254.

34.         K. Schroeter, D. Schröder, H. Schwarz, G. D. Reddy, O. Wiest, C. Carra, T. Bally: “Ion Chemistry of anti-o,o’-DibenzeneChemistry-Europ. J. 2000, 6, 4422-4430.

35.         D. J. Swinarski, O. Wiest: “Substituent Effects in Pericyclic Reactions of Radical Cations: The Ring Opening of 3-Substituted Cyclobutene Radical CationsJ. Org. Chem. 2000, 65, 6708-6714.



36.         N. Saettel, J. Oxgaard, O. Wiest: “Pericyclic Reactions of Radical CationsEurop J. Org. Chem. 2001, 1429-1439.

37.         J. El-Bahraoui, O. Wiest, D. Feichtinger, D. Plattner: “Rate Enhancement and Enantioselectivity in the Jacobsen-Katsuki Reaction: The Significance of the Sixth Coordination Site” Angew. Chem. Intl. Ed. Engl. 2001, 40, 2073-2076.

38.         U. H. Hirt, M. F. H. Schuster, A. N. French, O. Wiest, T. Wirth: “Chiral Hypervalent Iodine Compounds” Europ. J. Org. Chem. 2001, 6, 1569-1579.

39.         J. Peller, O. Wiest, P. V. Kamat: “Radiolysis and Sonolysis of 2,4 Dichlorophenoxyacetic Acid in Aqueous Solutions.OH Radical Mediated Degradation” J. Phys. Chem. B 2001, 105, 3176-3181.

40.         N. J. Saettel, O. Wiest: “DFT Study of the [2+2] Cycloreversion of Uracil Dimer Anion Radical: Waters Matter” J Am. Chem. Soc.2001, 123, 2693-2694.

41.         B. T. Shireman, M. J. Miller, M. Jonas, O. Wiest: “Conformational Study and Enantioselective, Regiospecific Syntheses of Novel Aminoxy trans-Proline Analogs Derived from Acylnitroso Diels-Alder CycloadditionJ. Org. Chem. 2001, 66¸ 6046-6056.

42.         A. T. Radosevich, O. Wiest: “Ab Initio Studies of the Ring-Closing Reaction of the Hexatriene Radical Cation” ” J. Org .Chem. 2001, 66¸ 5808-5813.

43.         O. Wiest: " Chemical Modelling: Applications and Theory. Volume 1." (Book Review) J. Am. Chem. Soc. 2001, 123, 9725-9726.

44.         J. Oxgaard, O. Wiest: “Symmetry, Radical Ions, and Butadienes: Exploring the Limits of Density Functional Theory” J. Phys. Chem. A 2001, 105,  8236-8240.

45.         H. Wandel, O. Wiest: “Enediynes in 11-membered rings - Synthesis and Structure of highly strained but unusually stable macrocycles J. Org. Chem. 2002, 67, 388-393.

46.         J. Oxgaard, O. Wiest “Rehybridized 1,3-Butadiene Radical Cations: How Far Will a Radical Cation Go to Maintain Conjugation? “J. Phys. Chem. A 2002 , 106, 3967-3974.

47.         M. J. Deetz, M. Jonas, C. Forbes, J. Malerich, B. D. Smith, O. Wiest: ” Unusually Low Barrier to Carbamate C-N Rotation” J. Org. Chem 2002, 67, 3949-3952.

48.         N. J. Saettel, O. Wiest, D. A. Singleton, M. P. Meyer: “Computational and experimental isotope effects of an electron transfer catalyzed cycloadditionJ. Am. Chem. Soc. 2002, 124, 11552-11559.

49.         S. B. Braun-Sand, O. Wiest: “Theoretical Studies of Mixed-Valence Transition Metal Complexes for Molecular Computing” J. Phys. Chem. A 2003, 107, 285-291.

50.         S. Braun-Sand, O. Wiest, J. El-Bahraoui: "Computational Studies of Molecular Electronic Devices" In: Molecules as Electronic Devices ACS Symposium Series Vol. 844 (Ed.: M. Lieberman) ACS, Washington, D.C. 2003, 230-242.

51.         A. R. Nicolaescu, O. Wiest, P. V. Kamat “Radical Induced Oxidative Transformation of QuinolineJ. Phys. Chem. A 2003, 107, 427-433.

52.         J. Peller, O. Wiest, P. V. Kamat: “Synergy of Combining Sonolysis and Photocatalysis in the Degradation and Mineralization of Chlorinated Aromatic Compounds” Environ. Sci Tech. 2003, 37, 1926-1932.

53.         J. Oxgaard, O. Wiest “Substituent Effects in the Vinylcyclopropane Radical Cation Rearrangement: A Computational Road to a New Synthetic Tool” Europ. J. Org, Chem, 2003, 1454-1462.

54.         O. Wiest, J. Oxgaard, N. J. Saettel “Structure and Reactivity of Hydrocarbon Radical CationsAdv. Phys. Org. Chem. 2003, 39, 87-109.

55.          N. J. Saettel, O. Wiest: Sterically Crowded Bicyclo[1.1.0]butane Radical CationsJ. Org. Chem. 2003, 68, 4549-4552.

56.         A. J. Oliver, O. Wiest, P. Helquist, M. J. Miller, M. Tenniswood: “Conformational and SAR Analysis of NAALADase and PSMA Inhibitors” Bioorg. Med. Chem. 2003, 11, 4455-4461.

57.         S. Braun-Sand, O. Wiest “Biasing Mixed-Valence Transition Metal Complexes: In Search of Bistable Complexes for Molecular Computing” J. Phys. Chem. B 2003, 107, 9624-9628.

58.         J. Peller, O. Wiest, P. V. Kamat: “ Mechanism of Hydroxyl Radical-Induced Breakdown of the Herbicide 2,4-Dichlorophenoxyacetic Acid (2,4-D)” Chemistry-Europ. J. 2003, 9, 5379-5387.

59.         M. Pauvert, P. Plaine, M. Jonas, O. Wiest: “Towards an Artificial Oxidative DNA PhotolyaseJ. Org. Chem. 2004, 69, 543-548.

60.         D.-F. Wang, O. Wiest, P. Helquist, H.-Y. Lan-Hargest, N. L. Wiech: “QSAR studies of PC-3 cell line inhibition activity of TSA and SAHA-like hydroxamic acids” Bioorg. Med. Chem. Lett. 2004, 13, 707-711.

61.         A. P.R. Zabell, P. Helquist, C. V. Stauffacher, O. Wiest “Computationally Designed Inhibitors of the Low Molecular Weight Phosphatase HCPTP” Bioorg. Med. Chem. 2004, 12, 1867-1880.

62.         O. Wiest, C. B. Harrison, M. Sax, N. J. Saettel, R. Cibulka,  B. König “Design, Synthesis, and Evaluation of a Biomimetic Artificial PhotolyaseJ. Org. Chem. 2004, 69,  8183-8185 (this paper was selected for the cover page of a December 2004 issue of JOC).

63.         D.-F. Wang, O. Wiest, P. Helquist, H.-Y. Lan-Hargest, N. L. Wiech: “On the Function of the 14Å Long Internal Cavity of Histone Deacetylase Like Protein: Implications for the Design of Histone Deacetylase InhibitorsJ. Med. Chem 2004, 47, 3409-3417.

64.         P. Ding, P. Helquist, Y. Chen, A. J. Oliver, O. Wiest, M. J. Miller “Synthesis of Conformationally Restricted Molecules as Potential NAALADase/PSMA Inhibitors” Organic Letters 2004 6, 1805-1808.

65.         J. Peller, O. Wiest;  P. V. Kamat “Hydroxyl Radical’s Role in the Remediation of a Common Herbicide, 2,4-Dichlorophenoxyacetic acid (2,4-D)” J. Phys. Chem B 2004, 108, 10925-10933.

66.         A. R. Nicolaescu, O. Wiest, P. V. Kamat “Mechanistic pathways of the hydroxyl radical reactions of quinoline. 1. Identification, distribution and yields of hydroxylated products” J. Phys. Chem. A 2005 109, 2822-2829

67.         A. R. Nicolaescu, O. Wiest, P. V. Kamat  Mechanistic pathways of the hydroxyl radical reactions of quinoline.  2. Computational analysis of .OH attack at C-atoms” J. Phys. Chem. A 2005, 109, 2829-2835.

68.         L. O’Neil, C. B. Harrison, O. Wiest “Computational Studies of DNA PhotolyaseJ. Phys. Chem. A 2005, 109, 7001-7012.

69.         E. Kieken, O. Wiest, P. Helquist, M. E. Cucciolito, G. Flores, A. Vitagliano, P.O. Norrby  Chiral diamine-silver(I)-alkene complexes: a quantum chemical and NMR study” Organometallics, 2005, 24, 3737-3745.

70.         D.-F. Wang, O. Wiest, P. Helquist, N. L. Wiech “Towards Selective HDAC Inhibitor Design:  Homology Modeling, Docking Studies, and Molecular Dynamics Simulations of Human ClassI HDACsJ. Med. Chem. 2005, 48, 6936-6947.

71.         S. K. Wright, M. DeClue, A. Mandal, L. Lee, O. Wiest, W. W. Cleland, D. Hilvert “Isotope Effects on the Enzymatic and Non-Enzymatic Reactions of ChorismateJ. Am. Chem. Soc. 2005, 127, 12957-12964.

72.         L. L. O’Neil, O. Wiest “A Selective, Non-Covalent Assay for Base Flipping in DNA” J. Am. Chem. Soc. 2005, 127, 16800-16801.



73.         N. Saettel, O. Wiest: “Hydrogen Bonding and Solvation Effects on the Cycloreversion of Uracil Dimers: a DFT Study” Tetrahedron 2006, 62, 6490-6500.

74.         A. P.R. Zabell, A. D. Schroff jr.; R. L. van Etten, O. Wiest,  C. V. Stauffacher “Crystal structure of human B-form low molecular weight phosphotyrosyl phosphatase at 1.6 Å resolution” J. Biol. Chem. 2006, 281, 6520-6527.

75.         P. Donoghue; O. Wiest, “Structure and Reactivity of Radical Cations: New Twists on Old Concepts” Chemistry- Europ. J. 2006, 12, 7018-7026.

76.         L. L. O’Neil, O. Wiest “Acyclic or Long-bond Intermediate in the ETC Dimerization of 4-Methoxystyrene” J. Org. Chem 2006, 71, 8926-8933.

77.         J. A. Weitgenant, I. Katsuyama, M. A. Bigi, S. J. Corden, J. T. Markiewicz, A. P. R. Zabell, K. T. Homan, O. Wiest, C. V. Stauffacher, P. Helquist “Synthesis of 5-Azaindole as a  Computationally Designed Inhibitor of the Low Molecular Weight Phosphatase HCPTP” Heterocycles 2006, 70, 599-607.

78.         K. C. Fortner, D. S. Laitar, J. Muldoon, S. B. Braun-Sand, O. Wiest, L. Pu, S. N. Brown “Ultrafast and Ultraslow Oxygen Atom Transfer Reactions Between Late Metal Centers” J. Am. Chem. Soc. 2007, 129, 588-600.

79.         P. Donoghue; P. Helquist, O. Wiest “Ligand and Substrate Effects on the Mechanism of Rhodium-Catalyzed Hydrogenation of EnamidesJ. Org. Chem. 2007, 72, 839-847.

80.         N. A. Valley, O. Wiest “Substitutent Effects in Radical Cation Diels-Alder Reactions” J. Org. Chem. 2007, 72, 559-566.

81.         D.-F. Wang, O. Wiest, P. Helquist “Zinc Binding in HDAC Inhibitors. A DFT Study” J. Org. Chem. 2007, 72, 5446-5449.

82.         P. J. Donoghue; E. Kieken, P. Helquist, O. Wiest “Development of a Q2MM Force field for the Silver Catalyzed Hydroamination of Alkynes” Adv. Synth. Catal. 20007, 349, 2647-2654.

83.         A. T. Johnson, O. Wiest “Structure and Dynamics of Poly(T) Single Strand DNA: Implications Toward CPD Formation” J. Phys. Chem. B 2007, 111, 14398-14404.

84.          L. L. O’Neil, A. Grossfield, O. Wiest “Base Flipping of the Thymine Dimer in Duplex DNA” J. Phys. Chem. B 2007, 111, 11843-11849.

85.               L. L. O’Neil, O. Wiest “Sequence dependence in base flipping: experimental and computational studies” Org. Biomol. Chem 2008, 6, 485-492.

86.               L. W. Chung, O. Wiest, Y. Wu “A Theoretical Study on the trans-Addition Intramolecular Hydroacylation of 4-Alkynals Catalyzed by Cationic Rhodium Complexes” J. Org. Chem. 2008, 73, 2649-2655

87.               L. L. O’Neil, O. Wiest “Structures and Energetics of Base Flipping of the Thymine Dimer Depend Upon DNA Sequence” J. Phys. Chem B. 2008, 112, 4113-4122.

88.               G. Estiu, E. Greenberg, C. B. Harrison, R. Mazitschek, J. E. Bradner, O. Wiest “On the structural origin of selectivity in Class II selective Histone Deacetylase Inhibitors” J. Med. Chem. 2008, 51, 2898-2906

89.               S. Weerasinghe, G. Estiu, O. Wiest, M. K. H. Pflum “Residues in the 11 Å Channel of Histone Deacetylase 1 Promote Catalytic Activity” J. Med. Chem. 2008, 51, 5543-5551.

90.               J. M. Plummer, J. A. Weitgenant, B. C. Noll, J. W. Lauher, O. Wiest, P. HelquistSynthesis, Structure, and Metal Complexation Behavior of a New Type of Functionalized Chiral Phenanthroline Derivatives” J. Org. Chem 2008, 73, 3911-3914.

91.               O’Daniel, P.; Jefferson, M.; Wiest, O. Seley-Radtke, K. L. “A Computational Study of Expanded Heterocyclic Nucleosides in DNA” J. Biomol. Struct. Dyn. 2008, 28, 283-292.

92.               C. S. Sevov, O. Wiest “Selectivity in the Electron Transfer Catalyzed Diels-Alder Reaction of (R)-a-Phellandrene and 4-Methoxystyrene” J. Org. Chem 2008, 73, 7909–7915

93.               P. J. Donoghue, P. Helquist, P. O. Norrby, O. Wiest ” Development of a Q2MM Force Field for the Asymmetric Rhodium Catalyzed Hydrogenation of EnamidesJ. Chem. Theor. Comp. 2008, 4 1313-1323.

94.               J. M. Carney, P. J. Donoghue, W. M. Wuest, O. Wiest, P. HelquistIntramolecular Hydroamination of Aminoalkynes with Silver-Phenanthroline Catalysts” Org. Lett 2008, 10, 3903-3906.

95.               P. J. Donoghue, P. Helquist, P. O. Norrby, O. Wiest ”Fast and Accurate Prediction of Enantioselectivity in Rhodium Catalyzed Hydrogenations” J. Am. Chem. Soc. 2009, 131, 410-411. (compare also Highlight in Angew. Chem. Intl. Ed. 2009, 48, 4476-4479)

96.               Bowers, A. L.; Greshok, T. J.; West, N.; Estiu, G., Schreiber, S. L.; Wiest, O.; Williams, R. M.; Bradner, J. E. “Synthesis and Conformation-Activity Relationships of the Peptide Isosteres of FK228 and LargazoleJ. Am. Chem. Soc. 2009, 131, 2900-2905.

97.               D.-S. Lee, H. Burd, J. Liu; E. Almaas, O. Wiest, A.-L. Barabasi, Z. N. Oltvai, V. Kapatral “Comparative genome-scale metabolic reconstruction and flux balance analysis of multiple Staphylococcus aureus genomes identify novel anti-microbial drug targets” J. Bact.2009, 191, 4015-4024

98.               N. L. Wiech, J. Fischer, P. Helquist, O. Wiest „Inhibition of Histone Deacetylases: a Pharmacological Approach to the Treatment of Non-Cancer DisordersCurr. Top. Med Chem. 2009 9, 257-271.

99.               Bowers, A. L.; West, N.; Newkirk, T. L.; Troutman-Youngman, A. E.;  Schreiber, S. L.; Wiest, O.; Bradner, J. E., Williams, R. M. “Synthesis and HDAC Inhibitory Activity of Largazole Analogs: Alteration of the Zinc-Binding Domain and Macrocyclic Scaffold” Org. Lett  2009, 11, 1301-1304.

100.            C. S. Sevov, O. Wiest “Selectivity in the Electron Transfer Catalyzed Diels-Alder Reactions” In: Wiley Series in Reactive Intermediates (M. Forbes, Ed.) Wiley & Sons, New York 2009.

101.            Charrier, C.; Gesson, J.-P.; Estiu, G.; Wiest, O.; Roche, J.; Bertrand, P. “Epigenetic Modulation Properties of New Benzofuranones Histone Deacetylases Inhibitors” J. Med. Chem 2009, 52, 3112-3115.

102.            P. Helquist, O. Wiest “Current Status of Drug Therapy Development for Niemann Pick Type C Disease” Drugs Fut. 2009, 34, accepted.

103.            O. Wiest “Methods and Non-Cancer Applications of HDAC Inhibition” Curr. Top. Med. Chem.2009, 9, 226.

104.            Y. Lan, L. Deng, J. Liu, C. Wang, O. Wiest, Z. Yang, Y.-D. Wu „On the Mechanism of the Palladium Catalyzed Intramolecular Pauson-Khand-Type Reaction” J. Org. Chem.2009, 74, ASAP.

105.            Cosner, C. C.; Markiewicz, J. YT.; Bourbon, P.; Mariani, C. J.; Wiest, O.; Huang, A.; Pipalia, N. H.; Rujoi, M.; Maxfield, F.; Helquist, P. “Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics” submitted for publication.

106.            J.C. Adams, M.J. Keiser, L. Basuino, H.F. Chambers, D.-S. Lee, O. Wiest, P.C. Babbitt  “The Chemical Diversity of Drugs from the Viewpoint of Small Molecule Metabolism “PLoS Computational Biology 2009, 5, accepted

107.            Y. Shen, J. Liu, G. Estiu, B. Isin, D-S. Lee, A-L. Barabási, V. Kapatral, O. Wiest, Z. N. Oltvai “A blueprint for antimicrobial hit discovery targeting metabolic networks” submitted for publication.