Fatty Acylated Proteins
Myristoylation: myristic acid (14:0 FA) linked to the
a-amino group of an N-terminal Gly; installed
co-translationally; stable
Palmitoylation: 16:0 FA attached via thioester linkage to a Cys residue; installed post-translationally
in the cytosol; reversible
Biological function: serve as membrane anchors;
Involved in protein intracellular targeting/signaling
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